New prenylated quinones from Peperomia galioides.

نویسندگان

  • V Mahiou
  • F Roblot
  • R Hocquemiller
  • A Cavé
  • A Rojas De Arias
  • A Inchausti
  • G Yaluff
  • A Fournet
چکیده

Two new prenylated quinones, piperogalone (1) and galopiperone (2), and a new prenylated dihydroquinone, hydropiperone (3), were isolated from Peperomia galioides H.B.K (Piperaceae). Hydropiperone exhibited potent antiparasitic activity against three species of Leishmania.

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منابع مشابه

In vitro and in vivo leishmanicidal studies of Peperomia galioides (Piperaceae).

Petroleum ether and methylene chloride extracts of Peperomia galioides and three prenylated diphenols, grifolic acid, grifolin and piperogalin exhibited in vitro antileishmanial activity. During the course of infection of BALB/c mice with Leishmania amazonensis, the treatments with each of these compounds did not influence the progression of the disease.

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عنوان ژورنال:
  • Journal of natural products

دوره 59 7  شماره 

صفحات  -

تاریخ انتشار 1996